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研究業績achievements

永田研究室のこれまでの研究業績です

論文 2015年 -


Maegawa, K., Watanabe, S., Noi, K., Okumura, M., Amagai, Y., Inoue, M., Ushioda, R., Nagata, K., Ogura, T. and Inaba, K.
The highly dynamic nature of ERdj5 is key to efficient elimination of aberrant protein oligomers through ER-associated degradation
Structure, in press(2017)

Morito D and Nagata K
Molecular Biology of Mysterin/RNF213
Current Topics in Environmental Health and Preventive Medicine, Part III, pp45-57 (2017)

Morito D and Nagata K
Physiological Role of Mysterin/RNF213 in Zebrafish
Current Topics in Environmental Health and Preventive Medicine, Part III, pp59-67 (2017)

Kotani Y, Morito D, Sakata K, Ainuki S, Sugihara M, Hatta T, Iemura SI, Takashima S, Natsume T,
Nagata K
Alternative exon skipping biases substrate preference of the deubiquitylase USP15 for
mysterin/RNF213, the moyamoya disease susceptibility factor
Scientific Reports 7, Article number: 44293 (2017)

Araki K, Ushioda R, Kusano H, Tanaka R, Hatta T, Fukui K, Nagata K, Natsume T
A crosslinker-based identification of redox relay targets
Anal. Biochem. 1;520:22-26. (2017)

Ito S, Nagata K.
Biology of Hsp47 (Serpin H1), a collagen-specific molecular chaperone.
Semin Cell Dev Biol. 2016 Nov 9. pii: S1084-9521(16)30384-6.

Ushioda R, Miyamoto A, Inoue M, Watanabe S, Okumura M, Maegawa KI, Uegaki K, Fujii S, Fukuda Y, Umitsu M, Takagi J, Inaba K, Mikoshiba K, Nagata K.
Redox-assisted regulation of Ca2+ homeostasis in the endoplasmic reticulum by disulfide reductase ERdj5.
Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6055-E6063.

Ishikawa Y, Ito S, Nagata K, Sakai LY, Bachinger HP.
Intracellular mechanisms of molecular recognition and sorting for transport of large extracellular matrix molecules.
Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6036-E6044.

D.J. Klionsky, K.Nagata, R.Ushioda et al.
Guidelines for the use and interpretation of assays for monitoring autophagy
Autophagy, 12(1): 1-222 (2016)

Ito S, Nagata K
Mutants of collagen-specific molecular chaperone Hsp47 causing osteogenesis imperfecta are structurally unstable with weak binding affinity to collagen.
Biochemical and Biophysical Research Communications, 469 (2016) 437e442

Kotani Y, Morito D, Yamazaki S, Ogino K, Kawakami K, Takashima S, Hirata H, Nagata K.
Neuromuscular regulation in zebrafish by a large AAA+ ATPase/ubiquitin ligase, mysterin/RNF213.
Scientific Reports 5, Article number: 16161 (2015)

Morito D, Nagata K
Pathogenic Hijacking of ER-Associated Degradation: Is ERAD Flexible?.
Mol Cell, 59(3), 335-344 (2015)

Kirstein-Miles J, Morito D, Kakihana T, Sugihara M, Minnen A, Hipp MS, Nussbaum-Krammer C, Hartl FU, Nagata K, Morimoto RI
Proteotoxic stress and ageing triggers the loss of redox homeostasis across cellular compartments.
EMBO J, e201591711 (2015)

Kawasaki K, Ushioda R, Ito S, Ikeda K, Masago Y, Nagata K
Deletion of the Collagen-specific Molecular Chaperone Hsp47 Causes Endoplasmic Reticulum Stress-mediated Apoptosis of Hepatic Stellate Cells.

J Biol Chem. 290. 3639-3646 (2015)

Avezov E, Konno T, Zyryanova A, Chen W, Laine R, Crespillo-Casado A, Melo E, Ushioda R, Nagata K, Kaminski CF, Harding HP, Ron D.
Retarded PDI diffusion and a reductive shift in poise of the calcium depleted endoplasmic reticulum
BMC Biol. 10;13(1):2(2015)

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