原著論文 1990年 - 1994年

T.Natsume, T.Koide, S.Yokota, K.Hirayoshi & K.Nagata
Interactions between collagen-binding stress protein HSP47 and collagen: Analysis of kinetic parameters by surface plasmon resonance Biosensor.
J Biol Chem. 269(49):31224-8 (1994)

O.Miyaishi, Y.Ito, K.Kozaki, T.Sato, H.Takechi, K.Nagata & S.Saga
Age-related attenuation of HSP47 heat response in fibroblasts.
Mech. Ageing and Develop. 77 :213-226 (1994)

N.Tsuboi, M.Ishikawa, Y.Tamura, S.Takayama, H.Tobioka, A.Matsuura, K.Hirayoshi, K.Nagata, N.Sato & K.Kikuchi
Monoclonal Antibody Specifically Reacting against 73-Kilodalton Heat Shock Cognate Protein: Possible Expression on Mammalian Cell Surface.
Hybridoma 13(5):373-381 (1994)

H.Masuda, M.Fukumoto, K.Hirayoshi & K.Nagata
Co-expression of the collagen-binding stress protein HSP47 gene and the α1(I) and α1(III) collagen genes in carbon tetrachloride-induced rat liver fibrosis.
J.Clin.Invest. 94(12):2481-2488 (1994)

T.Yamamoto, T.Ohno-Shosaku, E.Furukawa-Uenoyama, K.Nagata & Y.Okada
Electrostatic cell-to-cell adhesion by a non-proteolytic component in a protease preparation.
Cell Struct. Funct. 19(3):165-172 (1994)

T.Higashi, H.Takechi, Y.Uemura, H.Kikuchi & K.Nagata
Differential induction of mRNA species encoding several classes of stress proteins following focal cerebral ischemia in rats.
Brain Res. 650:239-248 (1994)

H.Kudo, K.Hirayoshi, Y.Kitagawa, S.Imamura & K.Nagata
Two collagen-binding proteins, osteonectin and HSP47, are coordinately induced in transformed keratinocytes by heat and other stresses.
Exptl. Cell Res. 212(2):219-224 (1994)

M.Yamaguchi, K.Hirayoshi, M.Ohkuma & K.Nagata
Enhancement of differentiation induction of mouse myelomonocytic leukemic cells by extracellular ATP.
J. Cell. Physiol. 159(3):441-449 (1994)

H.Takechi, N.Hosokawa, K.Hirayoshi, & K.Nagata
Alternative 5' splice site selection induced by heat shock.
Mol. Cell. Biol. 14(1):567-575 (1994)

S.Nishi, W.Taki, Y.Uemura, T.Higashi, H.Kikuchi, H.Kudoh, M.Satoh, & K.Nagata
Ischemic tolerance due to the induction of HSP70 in a rat ischemic recirculation model.
Brain Res. 615:281-288 (1993)

M.Satoh, A.NakaI, Y.Sokawa, K.Hirayoshi & K.Nagata
Modulation of the phosphorylation of glucose-regulated protein, GRP78, by and inhibition of glycosylation.
Exptl. Cell Res. 205(1):76-83 (1993)

K.Nagata & N.Hosokawa
Inhibition of Heat Shock Gene Expression by Flavonoids.
Stress Proteins. 15:86-92 (1993)

N.Hosokawa, H.Takechi, S.Yokota, K.Hirayoshi & K.Nagata
Structure of the gene encoding mouse 47-kDa heat-shock protein (HSP47).
Gene 126(1):187-193 (1993)

K.Nagata & N.Hosokawa
Flavonoids inhibit the expression of heat shock proteins and
the acquisition of thermotolerance: Inhibition of the activation of heat shock factor is a key mechanism.
In Hyperthermic Oncology 1992 (ed. E. W. Gerner & T. C. Cetas)
Taylor and Francis Inc. pp.57-63, 1993.

・M.Koishi, N.Hosokawa, M.Sato, A.Nakai, K.Hirayoshi, M.Hiraoka, M.Abe & K.Nagata
Quercetin, an inhibitor of heat shock protein synthesis, inhibits the acquisition of thermotolerance in a human colon carcinoma
cell line.
Jpn. J. Cancer Res. 83(11):1216-1222 (1992)

K.Nagata
Regulation and function of heat shock (stress) proteins.
In Hyperthermic Oncology in Japan, '91. (ed. R. Kamata)
Shinohara Publishers Inc., Tokyo, Japan, 1992, pp. 9-11.

M.Yamaguchi, M.Michishita, K.Hirayoshi, K.Yasukawa, M.Okuma & K.Nagata
Down-regulation of interleukin 6 receptors of mouse myelomonocytic leukemic cells by leukemia inhibitory factor.
J. Biol. Chem. 267(31):22035-22042 (1992)

N.Hosokawa, K.Hirayoshi, H.Kudo, H.Takechi, A.Aoike, K.Kawai & K.Nagata
Inhibition of the activation of heat shock factor in vivo and in vitro by flavonoids.
Mol. Cell. Biol. 12(8):3490-3498 (1992)

A.Nakai, M.Satoh, K.Hirayoshi & K.Nagata
Involvement of the stress protein HSP47 in procollagen processing in the endoplasmic reticulum.
J. Cell Biol. 117(4):903-914 (1992)

N.Kioka, N.Hosokawa, T.Komano, K.Hirayoshi, K.Nagata & K.Ueda
Quercetin, a bioflavonoid, inhibits the increase of human multidrug resistance gene (MDR1) expression caused by arsenite.
FEBS Lett. 301(3):307-309 (1992)

H.Takechi, K.HirayoshI, A.Nakai, H.Kudo, S.Saga & K.Nagata
Molecular cloning of a mouse 47-kDa heat-shock protein (HSP47), a collagen-binding stress protein, and its expression during the differentiation of F9 teratocarcinoma cells.
Eur. J. Biochem. 206(2):323-329 (1992)

N.Nakamura, A.Tsuru, K.Hirayoshi & K.Nagata
Purification and characterization of a vimentin-specific protease in mouse myeloid leukemia cells.
Eur. J. Biochem. 205(3):947-954 (1992)

K.Nagata, H.Takechi, H.Kudo, A.Nakai, M.Satoh & K.Hirayoshi
Regulation and function of collagen-binding heat shock protein: HSP47.
In Radiation Research (Eds. W.C.Dewey, M.Edington, R.J.M.Fry, E.J.Hall & G.F.Whitmore),Academic Press, 1992, pp. 976-979.

T.Sakata, S.Iwagami, Y.Tsuruta, M.Yamaguchi, M.Michishita, K.Nagata, Y.Takai, M.Ogata, H.Teraoka & H.Fujiwara
Constitutive expression of leukemia inhibitory factor (LIF) mRNA and production of LIF by a cloned murine thymic stromal cell line.
Thymus 19(1):89-95 (1992)

M.Koishi, N.Hosokawa, M.Satoh, A.Nakai, K.Hirayoshi, M.Hiraoka, M.Abe & K.Nagata
Quercetin, an inhibitor of the synthesis of heat shock proteins, prevents the acquisition of thermotolerance.
In Hyperthermic Oncology in Japan '90 (ed. K. Sekiba)
Asahi Printing and Publishing Co. 1991, pp. 289-290.

N.Hosokawa, M.Koishi & K.Nagata
Inhibitory effects of bioflavonoids on the expression of heat shock proteins.
In Hyperthermic Oncology in Japan '90 (ed. K. Sekiba)
Asahi Printing and Publishing Co. 1991, pp. 63-66.

K.Nagata, A.Nakai, N.Hosokawa, M.Kudo, H.Takechi, M.Satoh & K.Hirayoshi
Interaction of HSP47 with newly synthesized procollagen, and regulation of HSP expression.
In Heat Shock. (Eds. B.Maresca & S.Lindquist ), 1991, pp. 105-110.

S.Sassa & K.Nagata
Differentiation control in hematopoietic cells.
In The Status of Differentiation Therapy of Cancer. Vol. II. (Eds. S.Waxman, G.B. Rossi & F.Takaku), Raven Press, 1991, pp. 5-6.

M.Michishita, K.Hirayoshi, A.Tsuru, N.Nakamura, Y.Yoshida, M.Okuma & K.Nagata
Effect of type-β1 transforming growth factor on the proliferation and differentiation of mouse myelomonocytic leukemia cells (M1).
Exptl. Cell Res. 196(1):107-113 (1991)

K.Hirayoshi, H.Kudo, H.Takechi, A.Nakai, A.Iwamatsu, K.M.Yamada & K.Nagata
HSP47: a tissue-specific, transformation-sensitive, collagen-binding heat shock protein of chick embryo fibroblasts.
Mol. Cell. Biol. 11(8):4036-4045 (1991)

M.Michishita, M.Satoh, M.Yamaguchi, M.Okuma & K.Nagata
Phosphorylation of the stress protein HSP27 is an early event in murine myelomonocytic leukemic cell differentiation induced by leukemia inhibitory factor/D factor.
Biochem. Biophys. Res. Commun. 176(3):979-984 (1991)

K.Hirayoshi, A.Tsuru, M.Yamashita, Y.Yamamoto-Yamaguchi, K.Yasukawa, M.Hozumi, D.V.Goeddel & K.Nagata
Both D factor/LIF and IL-6 inhibit the differentiation of mouse teratocarcinoma F9 cells.
FEBS Lett. 82(2):401-404 (1991)

A.Nakai, M.Satoh, K.Hirayoshi & K.Nagata
Identification of the ATP-binding heat-inducible protein of Mr=37,000 as glyceraldehyde-3-phosphate dehydrogenase.
Biochem. Biophys. Res. Commun. 176(1):59-64 (1991)

N.Hosokawa, K.Hirayoshi, A.Nakai, Y.Hosokawa, N.Marui, M.Yoshida, T.Sakai, H.Nishino, A.Aoike, K.Kawai & K.Nagata
Flavonoids inhibit the expression of heat shock proteins.
Cell Struct. Funct.15(6):393-401 (1990)

K.Nagata, A.Nakai, M.Sato & K.Hirayoshi
Changes in the phosphorylation of BIP/GRP78 during malignant transformation.
In Hyperthermic Oncology in Japan 1989 (eds. T.Sugahara and M.Saito)
Taylor & Francis, London, 1990, pp.380-381.

A.Utani, T.Tanaka, C.Nishigori, Y.Miyachi, S.Imamura, M.Hosokawa, T.Takeda,
Another mechanism of the defect in type III collagen accumulation into the tissues of a patient with Ehlers-Danlos syndrome type IV: Increased intracellular degradation of type III procollagen.
Lab. Invest.63(2):181-188 (1990)

A.Nakai, C.Hirayama, K.Ohtsuka, K.HIrayoshi & K.Nagata
A novel ATP-binding heat inducible protein of Mr=37,000 that is sensitive to transformation in BALB/3T3 cells.
J. Cell. Physiol.143(3):577-589 (1990)

M.Michishita, Y.Yoshida, H.Uchino & K.Nagata
Induction of tumor necrosis factor-α and its receptors during differentiation of myeloid leukemia cells along the monocytic pathway. A possible regulatory mechanism for TNF-a production.
J. Biol. Chem.265(15): 8751-8759 (1990).

A.Tsuru, N.Nakamura, E.Takayama, Y.Suzuki, K.Hirayoshi & K.Nagata
Regulation of the expression of vimentin gene during the differentiation of mouse myeloid leukemia cells.
J. Cell Biol.110(5): 1655-1664 (1990).

S.Akiyama, K.Nagata & K.M.Yamada
Cell surface receptors for extracellular matrix components.
Biochim. Biophys. Acta (Reviews on Biomembranes)1031(1); 91-110 (1990)

A.Nakai, K.Hirayoshi & K.Nagata
Transformation of BALB/3T3 cells by simian virus 40 causes a decreased synthesis of a collagen- binding protein (hsp47).
J. Biol. Chem.265(2):992-999 (1990)

K.Ohtsuka, A.Masuda, A.Nakai & K.Nagata
A novel 40-kDa protein induced by heat shock and other stresses in mammalian and avian cells.
Biochem. Biophys. Res. Commun.166(2):642-647 (1990)

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