News

Cryo-EM structures of CDTa-bound CDTb-pore from Clostridioides difficile published in Nature Communications

We trapped the motion of CDTa in complex with CDTb-pore. Good work, Kawamoto-san and Yamada-kun!!

"Cryo-EM structures of the translocational binary toxin complex CDTa-bound CDTb-pore from Clostridioides difficile."
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Nature Research Microbiology Community blog — Behind the paper

"Posing just before protein translocation in bacterial binary toxin"
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Cryo-EM reveals Iota toxin (Ia-Ib) complex structure in Nature Structural & Molecular Biology

We revealed the protein translocation mechanism via the Ib-pore channel. Good work, Yamada-kun, Yoshida-san and Kawamoto-san!!

"Cryo-EM structures reveal translocational unfolding in the clostridial binary iota toxin complex."
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