原著論文 / Original articles
1991〜1995
・J.Yun, A.Tomida, K.Nagata & T.Tsuruo
Glucose-regulated stresses confer resistance to VP-16 in
human cancer cells through a decreased expression of DNA
topoisomerase II.
Oncology Research. 7(12):583-590 (1995)
・J.W.Davids, T.S.H.El-Thaher, A.Nakai, K.Nagata & A.D.Miller
Modeling the three-dimensional structure of serpin/molecular
chaperone HSP47.
Bioorganic Chemistry. 23:427-438 (1995)
・K.Yasuda, A.Nakai, T.Hatayama & K.Nagata
Cloning and expression of murine high-molecular-wight heat shock
proteins, HSP105.
J. Biol. Chem. 270(50):29718-29723 (1995)
・N.Nakamura, M.Shida, K.Hirayoshi & K.Nagata
Transcriptional regulation of the vimentin-encoding gene in mouse
myeloid leukemia M1 cells.
Gene. 166:281-286 (1995)
・A.Nakai, Y.Kawazoe, M.Tanabe, K.Nagata & R.I.Morimoto
The DNA-Binding properties of two heat shock factors, HSF1 and
HSF3, are induced in the avian erythroblast cell line HD6.
Mol. Cell. Biol. 15(10):5268-5278 (1995)
・T.Higashi, A.Nakai, Y.Umeda, H.Kikuchi & K.Nagata
Activation of heat shock factor 1 in rat brain during cerebral
ischemia or after heat shock.
Mol. Brain Res. 34:262-270 (1995)
・T.Higashi, S.Nishi, A.Nakai & K.Nagata
Regulatory mechanism of stress response in mammalian nervous
system during cerebral ischemia or after heat shock.
Neuropathology and Applied Neurobiology. 21:480-483 (1995)
・N.Nagai, A.Nakai & K.Nagata
Quercetin suppresses heat shock response by down regulation
of HSF1.
Biochem. Biophys. Res. Commun. 208(3):1099-1105 (1995)
・A.Nakai, T.Kawatani, S.Ohi, H.Kawasaki, T.Yoshimori, Y.Tashiro, Y.Miyata, I.Yahara,
M.Satoh & K.Nagata
Expression and phosphorylation of BiP/GRP78, a molecular
chaperone in the endoplasmic reticulum, during the differentiation
of a mouse myeloblastic cell line.
Cell Struct. Funct. 20:33-39 (1995)
・T.Natsume, T.Koide, S.Yokota, K.Hirayoshi & K.Nagata
Interactions between collagen-binding stress protein HSP47 and
collagen: Analysis of kinetic parameters by surface plasmon
resonance Biosensor.
J Biol Chem. 269(49):31224-8 (1994)
・O.Miyaishi, Y.Ito, K.Kozaki, T.Sato, H.Takechi, K.Nagata & S.Saga
Age-related attenuation of HSP47 heat response in fibroblasts.
Mech. Ageing and Develop. 77 :213-226 (1994)
・N.Tsuboi, M.Ishikawa, Y.Tamura, S.Takayama, H.Tobioka, A.Matsuura, K.Hirayoshi,
K.Nagata, N.Sato & K.Kikuchi
Monoclonal Antibody Specifically Reacting against 73-Kilodalton
Heat Shock Cognate Protein: Possible Expression on Mammalian
Cell Surface.
Hybridoma 13(5):373-381 (1994)
・H.Masuda, M.Fukumoto, K.Hirayoshi & K.Nagata
Co-expression of the collagen-binding stress protein HSP47 gene
and the α1(I) and α1(III) collagen genes in carbon tetrachloride-
induced rat liver fibrosis.
J.Clin.Invest. 94(12):2481-2488 (1994)
・T.Yamamoto, T.Ohno-Shosaku, E.Furukawa-Uenoyama, K.Nagata & Y.Okada
Electrostatic cell-to-cell adhesion by a non-proteolytic component
in a protease preparation.
Cell Struct. Funct. 19(3):165-172 (1994)
・T.Higashi, H.Takechi, Y.Uemura, H.Kikuchi & K.Nagata
Differential induction of mRNA species encoding several classes of
stress proteins following focal cerebral ischemia in rats.
Brain Res. 650:239-248 (1994)
・H.Kudo, K.Hirayoshi, Y.Kitagawa, S.Imamura & K.Nagata
Two collagen-binding proteins, osteonectin and HSP47, are
coordinately induced in transformed keratinocytes by heat and
other stresses.
Exptl. Cell Res. 212(2):219-224 (1994)
・M.Yamaguchi, K.Hirayoshi, M.Ohkuma & K.Nagata
Enhancement of differentiation induction of mouse myelomonocytic
leukemic cells by extracellular ATP.
J. Cell. Physiol. 159(3):441-449 (1994)
・H.Takechi, N.Hosokawa, K.Hirayoshi, & K.Nagata
Alternative 5' splice site selection induced by heat shock.
Mol. Cell. Biol. 14(1):567-575 (1994)
・S.Nishi, W.Taki, Y.Uemura, T.Higashi, H.Kikuchi, H.Kudoh, M.Satoh, & K.Nagata
Ischemic tolerance due to the induction of HSP70 in a rat ischemic
recirculation model.
Brain Res. 615:281-288 (1993)
・M.Satoh, A.NakaI, Y.Sokawa, K.Hirayoshi & K.Nagata
Modulation of the phosphorylation of glucose-regulated protein,
GRP78, by and inhibition of glycosylation.
Exptl. Cell Res. 205(1):76-83 (1993)
・K.Nagata & N.Hosokawa
Inhibition of Heat Shock Gene Expression by Flavonoids.
Stress Proteins. 15:86-92 (1993)
・N.Hosokawa, H.Takechi, S.Yokota, K.Hirayoshi & K.Nagata
Structure of the gene encoding mouse 47-kDa heat-shock protein
(HSP47).
Gene 126(1):187-193 (1993)
・K.Nagata & N.Hosokawa
Flavonoids inhibit the expression of heat shock proteins and
the acquisition of thermotolerance: Inhibition of the activation of
heat shock factor is a key mechanism.
In Hyperthermic Oncology 1992 (ed. E. W. Gerner & T. C. Cetas)
Taylor and Francis Inc. pp.57-63, 1993.
・M.Koishi, N.Hosokawa, M.Sato, A.Nakai, K.Hirayoshi, M.Hiraoka, M.Abe & K.Nagata
Quercetin, an inhibitor of heat shock protein synthesis, inhibits
the acquisition of thermotolerance in a human colon carcinoma
cell line.
Jpn. J. Cancer Res. 83(11):1216-1222 (1992)
・K.Nagata
Regulation and function of heat shock (stress) proteins.
In Hyperthermic Oncology in Japan, '91. (ed. R. Kamata)
Shinohara Publishers Inc., Tokyo, Japan, 1992, pp. 9-11.
・M.Yamaguchi, M.Michishita, K.Hirayoshi, K.Yasukawa, M.Okuma & K.Nagata
Down-regulation of interleukin 6 receptors of mouse
myelomonocytic leukemic cells by leukemia inhibitory factor.
J. Biol. Chem. 267(31):22035-22042 (1992)
・N.Hosokawa, K.Hirayoshi, H.Kudo, H.Takechi, A.Aoike, K.Kawai & K.Nagata
Inhibition of the activation of heat shock factor in vivo and in vitro
by flavonoids.
Mol. Cell. Biol. 12(8):3490-3498 (1992)
・A.Nakai, M.Satoh, K.Hirayoshi & K.Nagata
Involvement of the stress protein HSP47 in procollagen processing
in the endoplasmic reticulum.
J. Cell Biol. 117(4):903-914 (1992)
・N.Kioka, N.Hosokawa, T.Komano, K.Hirayoshi, K.Nagata & K.Ueda
Quercetin, a bioflavonoid, inhibits the increase of human multidrug
resistance gene (MDR1) expression caused by arsenite.
FEBS Lett. 301(3):307-309 (1992)
・H.Takechi, K.HirayoshI, A.Nakai, H.Kudo, S.Saga & K.Nagata
Molecular cloning of a mouse 47-kDa heat-shock protein (HSP47),
a collagen-binding stress protein, and its expression during the
differentiation of F9 teratocarcinoma cells.
Eur. J. Biochem. 206(2):323-329 (1992)
・N.Nakamura, A.Tsuru, K.Hirayoshi & K.Nagata
Purification and characterization of a vimentin-specific protease
in mouse myeloid leukemia cells.
Eur. J. Biochem. 205(3):947-954 (1992)
・K.Nagata, H.Takechi, H.Kudo, A.Nakai, M.Satoh & K.Hirayoshi
Regulation and function of collagen-binding heat shock protein:
HSP47.
In Radiation Research (Eds. W.C.Dewey, M.Edington, R.J.M.Fry, E.J.Hall &
G.F.Whitmore),Academic Press, 1992, pp. 976-979.
・T.Sakata, S.Iwagami, Y.Tsuruta, M.Yamaguchi, M.Michishita, K.Nagata, Y.Takai,
M.Ogata, H.Teraoka & H.Fujiwara
Constitutive expression of leukemia inhibitory factor (LIF) mRNA
and production of LIF by a cloned murine thymic stromal cell line.
Thymus 19(1):89-95 (1992)
・M.Koishi, N.Hosokawa, M.Satoh, A.Nakai, K.Hirayoshi, M.Hiraoka, M.Abe & K.Nagata
Quercetin, an inhibitor of the synthesis of heat shock proteins,
prevents the acquisition of thermotolerance.
In Hyperthermic Oncology in Japan '90 (ed. K. Sekiba)
Asahi Printing and Publishing Co. 1991, pp. 289-290.
・N.Hosokawa, M.Koishi & K.Nagata
Inhibitory effects of bioflavonoids on the expression of heat shock
proteins.
In Hyperthermic Oncology in Japan '90 (ed. K. Sekiba)
Asahi Printing and Publishing Co. 1991, pp. 63-66.
・K.Nagata, A.Nakai, N.Hosokawa, M.Kudo, H.Takechi, M.Satoh & K.Hirayoshi
Interaction of HSP47 with newly synthesized procollagen,
and regulation of HSP expression.
In Heat Shock. (Eds. B.Maresca & S.Lindquist ),
1991, pp. 105-110.
・S.Sassa & K.Nagata
Differentiation control in hematopoietic cells.
In The Status of Differentiation Therapy of Cancer. Vol. II. (Eds. S.Waxman,
G.B. Rossi & F.Takaku), Raven Press, 1991, pp. 5-6.
・M.Michishita, K.Hirayoshi, A.Tsuru, N.Nakamura, Y.Yoshida, M.Okuma & K.Nagata
Effect of type-β1 transforming growth factor on the proliferation
and differentiation of mouse myelomonocytic leukemia cells (M1).
Exptl. Cell Res. 196(1):107-113 (1991)
・K.Hirayoshi, H.Kudo, H.Takechi, A.Nakai, A.Iwamatsu, K.M.Yamada & K.Nagata
HSP47: a tissue-specific, transformation-sensitive, collagen-
binding heat shock protein of chick embryo fibroblasts.
Mol. Cell. Biol. 11(8):4036-4045 (1991)
・M.Michishita, M.Satoh, M.Yamaguchi, M.Okuma & K.Nagata
Phosphorylation of the stress protein HSP27 is an early event
in murine myelomonocytic leukemic cell differentiation induced
by leukemia inhibitory factor/D factor.
Biochem. Biophys. Res. Commun. 176(3):979-984 (1991)
・K.Hirayoshi, A.Tsuru, M.Yamashita, Y.Yamamoto-Yamaguchi, K.Yasukawa,
M.Hozumi, D.V.Goeddel & K.Nagata
Both D factor/LIF and IL-6 inhibit the differentiation of mouse
teratocarcinoma F9 cells.
FEBS Lett. 82(2):401-404 (1991)
・A.Nakai, M.Satoh, K.Hirayoshi & K.Nagata
Identification of the ATP-binding heat-inducible protein of
Mr=37,000 as glyceraldehyde-3-phosphate dehydrogenase.
Biochem. Biophys. Res. Commun. 176(1):59-64 (1991)